Parameterless detection of liquid–liquid interfaces with sub-micron resolution in single-molecule localization microscopy
A new method using a maximum likelihood estimator (MLE) is able to detect the location of soft interfaces, such as the oil–water interface, with high precision in single-molecule localization microscopy (SMLM) experiments. The method remains effective even if the interface contains, but is not saturated with, particles.
Aug 1, 2022
