Single-particle geometries of pharmaceutical powders from X-ray tomography; a simple and reliable sample preparation method
This paper presents a simple method for abtaining unambiguous particle sizes and shapes for particles on the microscale.
Jun 1, 2025
YADE - An extensible framework for the interactive simulation of multiscale, multiphase, and multiphysics particulate systems
This paper presents the key elements of YADE, an open-source software for discrete element method (DEM) simulations.
Nov 1, 2024
Tablet ejection: A systematic comparison between force, static friction, and kinetic friction
This study present a new method to measure both static and kinetic friction between the tablet and die wall during ejection.
Aug 1, 2024
Multi-component mixing and demixing model for predictive finite element modelling of pharmaceutical powder compaction
Using experimental data on only a few powder mixtures, it is possible to do predictive finite element method (FEM) simualtions of the entire formulation design space.
Jul 1, 2024
Volume-interacting level set discrete element method: The porosity and angle of repose of aspherical, angular, and concave particles
Through a numerical study, this work shows that particle shape, particularly concavity and sharp features, can have a drastic effect on bulk properties.
Jan 1, 2024
A physically consistent Discrete Element Method for arbitrary shapes using Volume-interacting Level Sets
A new variant of the discrete element method (DEM) with extensive testing, working on highly complex shapes such as those that are concave and interlocking.
Sep 1, 2023
Parameterless detection of liquid–liquid interfaces with sub-micron resolution in single-molecule localization microscopy
A new method using a maximum likelihood estimator (MLE) is able to detect the location of soft interfaces, such as the oil–water interface, with high precision in single-molecule localization microscopy (SMLM) experiments. The method remains effective even if the interface contains, but is not saturated with, particles.
Aug 1, 2022
Predictive modelling of powder compaction for binary mixtures using the finite element method
Detailed stress profiles for tablets of various compositions can be predicted using only data on component powders. Softer materials near the die wall might reduce radial pressures that frequently yield defects.
May 1, 2022
Closed-Form Coexistence Equation for Phase Separation of Polymeric Mixtures in Dissipative Particle Dynamics
The coexistence equation presentend in this work, based on the Flory-Huggins model, can be used for the coarse-graning of polymeric mixtures while preserving their overal phase behaviour.
Jul 1, 2021